Research into conolidine has triggered discovery of an opioid receptor in the human body referred to as ACKR3/CXCR7. ACKR3 is apparently essentially the most popular focus on for conolidine, which also disregards another 4 classical opioid receptors(three).Conolidine has become present in the tabernaemontana divaricata plant, that is during the Ap